Arteriocyte is now a part of Isto Biologics.

ISTO Products

Our novel solutions for rapid bone healing are changing the field of spine and orthopedic treatments.

ISTO’s Mission

Developing the New Standards of Care

ISTO is focused on using cutting-edge science to develop novel orthobiologic products that are safe, efficacious, and cost-effective. Our groundbreaking bone growth portfolio has already improved the quality of life for countless patients. Each day brings new discoveries and innovations that will help doctors restore mobility, reduce pain, and improve the quality of life for their patients.

The Solution Pipeline

Three of ISTO’s groundbreaking products are already in-use, and surgeons anticipate two others to clear clinical trials.

Clinical Trials


Bone Graft Extender & Substitute

InQu, a novel biosynthetic bone graft, creates a natural microenvironment that promotes new bone formation in spinal fusions and orthopedic procedures. With superb handling characteristics and predictable resorption, InQu offers benefits for a variety of applications.

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Cell-Based Therapy

NuQu is an injectable treatment designed to relieve back pain by stopping the progression of degenerative disc disease and repairing the degenerated disc.

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Trabecular Bone Graft

Influx is a natural bone graft material made of 100% demineralized trabecular bone. It provides an osteoinductive, flexible scaffold that promotes cell growth, making it ideal for a variety of spinal and orthopedic surgeries.

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Regenerative Cartilage Technology

ISTO is developing RevaFlex as a novel cartilage implant that may offer a groundbreaking alternative to current knee restoration options. It is designed to reduce pain and restore function to the knee by regenerating healthy and durable cartilage.

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Concentrated Bone Marrow Aspirate System

Using a simple, automated process, the CellPoint system enables clinicians to quickly recover patient-derived nucleated cells, platelets, and other soluble factors in the form of concentrated bone marrow aspirate.

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The Pace of Innovation

“Our unique biologics portfolio offers bone-healing solutions for today, while our pipeline focuses on proprietary technology for cartilage repair tomorrow. It’s all in an effort to create less invasive ways to more rapidly heal patients.”

Phillip Kuhn, ISTO Chief Commercial Officer

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