Influx™ SPARC is a fully pliable, cellular-enrichedallograft with a high concentration of growth factors for use in bone repair or reconstruction.
advanced technologies set SPARC apart
Fully demineralized cortical fibers
Contribute highly conductive, natural scaffold for new bone generation1
Advanced Cell Cleansing
Proprietary processing preserves osteoprogenitor cells while removing red and white blood cells
Marrow-derived cells are contained in cancellous chips
Cortical fiber DBMs provide high quality osteoinductive signal2
Additional growth factors are captured from bone lining cells and restored back into the product
EASE OF USE
10-minute thaw time in room temperature water bath
DMSO Free: Immediately implantable upon thawing in a ready-to-use syringe
Cells. SIgnal. SPARC.
SPARC is an advanced, next generation Cellular Bone Matrix (CBM) that incorporates essential components for new bone development. A key advantage of SPARC is the conserved concentration of signal and cells necessary for bone formation.
SPARC contains added growth factors captured from bone lining cells that are typically discarded in washing away the marrow of the cortical shaft. Native growth factors that can promote induction, angiogenesis, and scaffold proliferation and integration are found in SPARC and are some key contributors for the formation of bone.3 In the processing phase, these growth factors are amplified above baseline and are available to contribute signaling for bone growth. SPARC PROVIDES ADDED GROWTH FACTORS3
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Isto Biologics is the trade name of a single integrated business group that operates through a number of subsidiaries that includes Arteriocyte Medical Systems, Inc., Isto Technologies II, LLC, Progenicare, LLC, Progenicare Therapeutics, LLC, and Advanced Transfusion Services, LLC.