Influx™ SPARC is a fully pliable, cellular-enrichedallograft with a high concentration of growth factors for use in bone repair or reconstruction.
advanced technologies set SPARC apart
Cortical Fibers have undergone a demineralization process
Contribute highly conductive, natural scaffold for new bone generation1
Advanced Cell Cleansing
Proprietary processing preserves osteoprogenitor cells while removing red and white blood cells
Bone-derived cells are contained in cancellous chips
Cortical fiber DBM provides high quality osteoinductive signal2
Additional growth factors are preserved from bone lining cells and retained within the final product
EASE OF USE
10-minute thaw time in room temperature water bath
DMSO Free: Immediately implantable upon thawing in a ready-to-use syringe
Cells. SIgnal. SPARC.
SPARC is an advanced, next generation Cellular Bone Matrix (CBM) that incorporates essential components for new bone development. A key advantage of SPARC is the conserved concentration of signal and cells necessary for bone formation.
SPARC contains growth factors captured from bone lining cells that are typically discarded in washing away the bone stroma of the cancellous bone. Native growth factors that can promote induction, angiogenesis, and scaffold proliferation and integration are found in SPARC and are some key contributors for the formation of bone.3 In the processing phase, these growth factors are preserved and available to contribute signaling for bone growth. SPARC RESTORES GROWTH FACTORS3
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Isto Biologics is the trade name of a single integrated business group that operates through a number of subsidiaries that includes Arteriocyte Medical Systems, Inc., Isto Technologies II, LLC, Progenicare, LLC, Progenicare Therapeutics, LLC, and Advanced Transfusion Services, LLC.