Supporting Publications

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Hernigou P, et al. Local transplantation of bone marrow concentrated granulocytes precursors can cure without antibiotics infected non-union of polytraumatic patients in absence of bone defect. Int Orthop. 40:2331-2338, 2016.

Patel AN, et al. Evaluation of autologous platelet rich plasma for cardiac surgery: outcome analysis of 2000 patients. J Cardiothorac Surg. 2016. 11(1):62. doi: 10.1186/s13019-016-0452-9

Aronowitz JA, et al. Mechanical versus enzymatic isolation of stromal vascular fraction cells from adipose tissue. Springerplus. 4:713. 2015. doi: 10.11861540064-015-1509-2.

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Iafrati, M.D., et al. Early results and lessons learned from a multicenter, randomized, double-blind trial of bone marrow aspirate concentrate in critical limb ischemia. Journal of Vascular Surgery. 54(6): 1650-1658. 2011.

Liang TW, et al. Autologous bone marrow mononuclear cell therapy for critical limb ischemia is effective and durable. J Vasc Surg. 63(6): 1541-1546. 2016.

Ponemone V, et al. Safety and effectiveness of bone marrow cell concentrate in the treatment of chronic critical limb ischemia utilizing a rapid point-of-care system. Stem Cells Int. 2017 doi: 10.1155/2017/413762

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Ganji V, et al. Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells: a pilot study. Journal of Bone and Joint Surgery. 1153-1160. 2004.

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Hernigou P, et al. Cancer risk is not increased in patients treated for orthopaedic diseases with autologous bone marrow cell concentrate. J Bone Joint Surg Am. 95 (24): 2215-2221. 2013.

Hernigou P, Poignard A, Beaujean F, and Rouard H. Percutaneous autologous bone marrow grafting for nonunions. Influence of the number and concentration of progenitor cells. J Bone Joint Surg Am. 87:1430-1437. 2005.

Haufe SMW and Mork AR. Intradiscal injection of hematopoietic stem cells in an attempt to rejuvenate the intervertebral disc. Stem Cells Dev. 15:136-137. 2006.

Pettine KA, et al. Percutaneous injection of autologous bone marrow concentrate cells significantly reduces lumbar discogenic pain through 12 months. Stem Cells. 33:146-156. 2015.

Tuakli-Worsonu YA, et al. Lumbar intradiskal platelet-rich plasma (PRP) injections: A prospective, double blind, randomized controlled study. PMR doi: 10.1016/j.pmrj. 2015.08.010, 2016.

Ajiboye, R.M., et al. Clinical and radiographic outcomes of concentrated bone marrow aspirate with allograft and demineralized bone matrix for posterolateral and interbody lumbar fusion in elderly patients. Eur Spine J. 24: 2567. 2015. doi:10.1007/s00586-015-4117-5.

Gan Y, et al. The clinical use of enriched bone marrow stem cells combined with porous beta-tricalcium phosphate in posterior spinal fusion. Biomaterials. (29): 3973-3982. 2008.

Hart R, et al. Allograft alone versus allograft with bone marrow concentrate for the healing of the instrumented posterolateral lumbar fusion. Spine J. 14(7): 1318-1324. 2014.

Johnson, RG. Bone marrow concentrate with allograft equivalent to autograft in lumbar fusions. Spine. 39(9): 695-700. 2014.

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Franklin, S. et al. The use of platelet-rich plasma for percutaneous treatment of tendinopathies. Operative Techniques in Orthopaedics. 2013;23(2):63-68.

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Podesta L, et al. Treatment of partial ulnar collateral ligament tears in the elbow with platelet-rich plasma. The American Journal of Sports Medicine. 2013;41(7):1689-94. doi: 10.1177/0363546513487979

Scollon-Grieve KL, et al. Platelet-rich plasma injection for partial tendon tear in a high school athlete: a case presentation. American Academy of Physical Medicine and Rehabilitation. 2011;3(4):391-5. doi: 10.1016/j.pmrj.2010.11.008

Sampson S, et al. Platelet-rich plasma therapy as a first line treatment for severe Achilles tendon tear: a case report. International Journal of Therapy and Rehabilitation. 2011;18(2):101-106.

Wilson JJ, et al. Platelet-rich plasma for the treatment of chronic plantar fasciopathy in adults: a case series. Foot & Ankle Specialist. 2014;7:61-7. doi: 10.1177/1938640013509671

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Hannon CP, et al. Arthroscopic bone marrow stimulation and concentrated bone marrow aspirate for osteochondral lesions of the talus: a case-control study of functional and magnetic resonance observation of cartilage repair tissue outcomes. Arthroscopy. 2016;32(2): 339-347.

Krych A, et al. Bone marrow concentrate improves early cartilage phase maturation of a scaffold plug in the knee: a comparative magnetic resonance imaging analysis to platelet-rich plasma and control. Am J Sports Med. 2016;44: 91. DOI: 10.1177/0363546515609597

Lee GW, et al. Is platelet-rich plasma able to enhance the results of arthroscopic microfracture in early osteoarthritis and cartilage lesion over 40 years of age? Eur J Orthop Surg Traumatol. 2013;23(5):581-7. doi:10.1007/s00590-012-1038-4

Rodriguez-Collazo ER, et. al. Combined use of the Ilizarov method, concentrated bone marrow aspirate (cBMA), and platelet-rich plasma (PRP) to expedite healing of bimalleolar fractures. Strategies in Trauma and Limb Reconstruction. 2015;10(3):161-166. doi: 10.1007/s11751-015-0239-x

Rodriguez-Collazo ER, et al. A retrospective look at integrating a novel regenerative medicine approach in plastic limb reconstruction. Plast Reconstr Surg Glob Open. 2017;5(1):e1214. doi: 10.1097/GOX.0000000000001214

Rodriguez-Collazo ER. Combined use of the illizarov method, concentrated bone marrow aspirate. Orthopedics & Rheumatology. 2015;1(3): 555561.

Rodriguez-Collazo ER, et al. Bone marrow concentrate enriched in platelet growth factors combined with de-mineralized bone matrix for complex revision and complex lower limb arthrodesis. Orthop Rheumatol Open Access J. 2015;1(2): 555558.

Rodriguez-Collazo ER, et al. Combined use of the Ilizarov method, concentrated bone marrow aspirate (cBMA), and platelet-rich plasma (PRP) to expedite healing of bimalleolar fractures. Strat Traum Limb Recon. 2015;10:161-166. DOI 10.1007/s11751-015-0239-x

Skoff HD. Revision rotator cuff reconstruction for large tears with retraction: a novel technique using autogenous tendon and autologous marrow. Am J Orthop. 2015;44(7):326-331.

Smyth N, et al. The effect of platelet-rich plasma on autologous osteochondral transplantation: an in vivo rabbit model. J Bone Joint Surg Am. 2013 Dec 18;95(24):2185-93. doi: 10.2106/JBJS.L.01497

Vavken P, et al. The effect of platelet concentrates on graft maturation and graft-bone interface healing in ACL reconstruction in human patients: A systematic review of controlled trials. Arthroscopy. 2011;27(11):1573-83. doi: 10.1016/j.arthro.2011.06.003

Vogrin M, et al. The effect of platelet-derived growth factors on knee stability after anterior cruciate ligament reconstruction: a prospective randomized clinical study. Wien Klin Wochenschr. 2010;122 (2): 91–95. doi: 10.1007/s00508-010-1340-2

Zavadil D, et al. Autologous platelet gel and platelet poor plasma reduce pain with total shoulder arthroplasty. JECT. 2007;39:177–182.

Zhong W, et al. In vivo comparison of the bone regeneration capability of human bone marrow concentrates vs. Platelet-rich plasma. PLoS ONE. 2012;7(7): e40833. doi:10.1371/journal.pone.0040833

Boakye L, et al. Platelet-rich plasma increases transforming growth factor-beta1 expression at graft-host interface following autologous osteochondral transplantation in a rabbit model. World J Orthop. 2015; 6(11): 961-969. DOI: 10.5312/wjo.v6.i11.961

Cassano JM, et al. Bone marrow concentrate and platelet-rich plasma differ in cell distribution and interleukin 1 receptor antagonist protein concentration. Knee Surg Sports Traumatol Arthrosc. 2016. doi: 10.1007/s00167-016-3981-9

Castillo TN, et al. Comparison of growth factor and platelet concentration from commercial platelet-rich plasma separation systems. Am J Sports Med. 2011;39(2):266-71. doi: 10.1177/036354651038751

Christensen K, et al. Autologous platelet gel: an in vitro analysis of platelet-rich plasma using multiple cycles. JECT. 2006;38:249–253.

Degen RM, et al. Commercial separation systems designed for preparation of platelet-rich plasma yield differences in cellular composition. HSS J. 2017;13(1):75-80. doi: 10.1007/s11420-016-9519-3

Dhurat R, et al. Principles and methods of preparation of platelet-rich plasma: a review and author's perspective. J Cutan Aesthet Surg. 2014;7(4):189-97. doi: 10.4103/0974-2077.150734

Dohan E, et al. Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF). Trends Biotechnol. 2009;27(3):158-67. doi: 10.1016/j.tibtech.2008.11.009

Fitzpatrick J, et al. Analysis of platelet-rich plasma extraction variations in platelet and blood components between 4 common commercial kits. Orthop J Sports Med. 2017;5(1):2325967116675272. doi: 10.1177/2325967116675272

Gersch RP. Platelet rich plasma augments adipose-derived stem cell growth and differentiation. Aesthet Surg J. 2017;1;37(6):723-729. doi: 10.1093/asj/sjw235

Joshi SU, et al. Patient-derived and intraoperatively formed biomaterial for tissue engineering. Methods Mol Biol. 2017;1553:265-272. doi: 10.1007/978-1-4939-6756-8_21

Kelc R, et al. Platelet-rich plasma, especially when combined with a TGF-β inhibitor promotes proliferation, viability and myogenic differentiation of myoblasts in vitro. PLoS ONE. 10(2):e0117302. doi:10.1371/journal.pone.0117302

McDaniel JS, et al. Alternatives to autograft evaluated in a rabbit segmental bone defect. Int Orthop. 2016;40(1):197-203. doi: 10.1007/s00264-015-2824-5

Mishra A, et al. Buffered platelet-rich plasma enhances mesenchymal stem cell proliferation and chondrogenic differentiation. Tissue Engineering. 2009;15(3):431-5. doi: 10.1089/ten.tec.2008.0534

Ogura T, et al. A novel method of preparing platelet-rich plasma (PRP): an automatic blood separation device “Magellan.” Wound Repair and Regeneration. 2013. 21(1):A2.

O’Shea CM, et al. Comparison of platelet counting technologies in equine platelet concentrates. Vet Surg. 2015;44(3):304-13. doi: 10.1111/j.1532-950X.2014.12290.x

Pochini A de C, et al. Analysis of cytokine profile and growth factors in platelet-rich plasma obtained by open systems and commercial columns. Einstein. 2016;14(3):391-397. doi:10.1590/S1679-45082016AO3548

Betsch M, et al. Bone marrow aspiration concentrate and platelet rich plasma for osteochondral repair in a porcine osteochondral defect model. PLOS One. 8(8): e71602. 2013.

Cassano, J.M., Kennedy, J.G., Ross, K.A. et al. Bone marrow concentrate and platelet-rich plasma differ in cell distribution and interleukin 1 receptor antagonist protein concentration. Knee Surg Sports Traumatol Arthrosc. 2016. doi:10.1007/s00167-016-3981-9

Englert S, et al. Autologous platelet gel applications during cardiovascular surgery: effect on wound healing. JECT. 2005;37:148–152.

Hom D, et al. The healing effects of autologous platelet gel on acute human skin wounds. Arch Facial Plast Surg. 2007; 9(3):174-83. doi: 10.1001/archfaci.9.3.174

Kakudo N, et al. The use of autologous platelet-rich plasma in the treatment of intractable skin ulcer: A case series. Open Journal of Regenerative Medicine. 2012; 01(03):29-32. doi: 10.4236/ojrm.2012.13005

Litmathe J, et al. The use of autologous platelet gel (APG) for high-risk patients in cardiac surgery – is it beneficial? Perfusion. 2009. 24(6):381-7. doi: 10.1177/0267659109358283

Patel AN, et al. Evaluation of autologous platelet rich plasma for cardiac surgery: outcome analysis of 2000 patients. J Cardiothorac Surg. 2016. 11(1):62. doi: 10.1186/s13019-016-0452-9

Saratzis N, et al. Non-activated autologous platelet-rich plasma for the prevention of inguinal wound-related complications after endovascular repair of abdominal aortic aneurysms. J Extra Corpor Technol. 2008; 40(1):52-6.

Vang S, et al. Autologous platelet gel in coronary artery bypass grafting: effects on surgical wound healing. JECT. 2007;39:31–38.

Brady C, et aI. Use of autologous platelet gel in bariatric surgery. J Extra Corpor Technol. 2006; 38:161-164.

Cervelli V, et al. P.R.L. Platelet rich lipotransfert: our experience and current state of art in the combined use of fat and PRP. Biomed Res Int. 2013. doi: 10.1155/2013/434191

Gentile P, et al. A comparative translational study: the combined use of enhanced stromal vascular fraction and platelet-rich plasma improves fat grafting maintenance in breast reconstruction. Stem Cells Transl Med. 2012;1(4):341-51. doi: 10.5966/sctm.2011-0065

Rademakers LM, et al. Stability of an autologous platelet clot in the pericardial sac: An experimental and clinical study. J Thorac Cardiovasc Surg. 2009;137(5):1190-4. doi: 10.1016/j.jtcvs.2008.10.012

Wehberg KE, et al. Intramyocardial injection of autologous platelet-rich plasma combined with transmyocardial revascularization. Cell Transplant. 2009;18(3):353-9. doi: 10.3727/096368909788534988