Magellan References
  1. AMSI Source: TS-0078-182.

  2. Patel A, et al. Evaluation of autologous platelet-rich plasma for cardiac surgery: outcome analysis of 2000 patients. J Cardiothorac Surg. 2016. 11(1):62. doi: 10.1186/s13019-016-0452-9.

  3. Castillo T, et al. Comparison of growth factor and platelet concentration from commercial platelet-rich plasma separation systems. The American Journal of Sports Medicine. 2011. 39(2):266-271.

  4. Shapiro S, et al. A prospective, single-blind, placebo-controlled trial of bone marrow aspirate concentrate for knee osteoarthritis. The American Journal of Sports Medicine. 2017. 45(1):82-90. doi: 10.1177/0363546516662455.

  5. Cassano JM, et al. Bone marrow concentrate and platelet-rich plasma differ in cell distribution and interleukin 1 receptor antagonist protein concentration. Knee Surg Sports Traumatol Arthrosc. 2016. doi: 10.1007/s00167-016-3981-9.

  6. Pittenger MF, et al. Multilineage potential of adult human mesenchymal stem cells. Science. 1999. 284(5411):143-147. doi: 10.1126/science.284.5411.143.

  7. Kalka C, et al. Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. PNAS. 2000. 97(7):3422-3427.

  8. Bessler H, et al. Postoperative pain, morphine consumption, and genetic polymorphism of IL-1β and IL-1 receptor antagonist. Neuroscience Letters. 2006. 404(1-2):154-158.

  9. AMSI Source: TS-001A-008.

  10. AMSI Source: TS-0078-103.

Back to top


InQu References
  1. Chedid MK, Tundo KM, Block JM, Muir JM. Hybrid biosynthetic autograft extender for use in posterior lumbar interbody fusion: safety and clinical effectiveness. Open Orthop J. 2015;9:218-225. doi: 10.2174/1874325001509010194.

  2. Solchaga LA, Dennis JE, Goldberg VM, Kaplan AI. Hyaluronic acid-based polymers as cell carriers for tissue-engineered repair of bone and cartilage. J Orthop Res. 1999;17:205-213. doi: 10.1002/jbm.10011.

  3. Kim HD, Valentini RF. Retention and activity of BMP-2 in hyaluronic acid-based scaffolds in vitro. J Biomed Mater Res. 2002;59(3): 573-84. doi: 10.1002/jbm.10011.

  4. Stewart G, Gage GB, Neidert G, Adkisson HD IV. Within patient radiological comparative analysis of the performance of two bone graft extenders utilized in posterolateral lumbar fusion: a retrospective case series. Front Surg. 2016;2(69). doi: 10.3389/fsurg.2015.00069.

  5. Grande D; North Shore Hospital. In vitro cell binding assay results; unpublished, independent data.

  6. Hsu EL, Ghodasra JH, Ashtekar A, et al. A comparative evaluation of factors influencing osteoinductivity among scaffolds designed for bone regeneration. Tissue Eng Part A. 2013;19(15-16):1764-1771. doi: 10.1089/ten. TEA.2012.0711.

  7. Bohner M. Siliconsubstituted calcium phosphates - a critical review. Biomaterials. 2009;30(32):6403-6406. doi: 10.1016/j.biomaterials.2009.08.007.

  8. Walsh WR, Oliver RA, Gage G, et al. Application of resorbable poly(lactide-co-glycolide) with entangled hyaluronic acid as an autograft extender for posterolateral intertransverse lumbar fusions in rabbits. Tissue Eng Part A. 2011;17(1-2):213-220. doi: 10.1089/ten.TEA.2010.0008.

  9. Harris TE. Treatment of long bone fractures and nonunion using InQu Bone Graft Extender & Substitute.

  10. Kerzner, MS. A radiographic and clinical retrospective case series of high risk foot & ankle procedures (Charcot reconstruction) using InQu Bone Graft Substitute.

Back to top


Influx Demineralized Bone Matrix
  1. Martin GJ, et. Al.Spine, 1999, 24, 637-645.

  2. Data on file, DCIDonor Services Tissue Bank.

  3. Muschler GF. J Bone Joint Surg Am. 1997, 79, 1699-1709.

  4.  Data on file at Xtant Medical.

Influx SPARC
  1. Martin GJ, et. Al.Spine, 1999, 24, 637-645.

  2. Urist, M.R. (2009). The Classic: A Morphogenetic Matrix for Differentiation of Bone Tissue. Clin Orthop Relat Res. 467:3068-3070.

  3. Data on file, Advanced Biologics

Influx PLUS
  1. Data on file at Xtant Medical.

  2. Kiely, P.D. et al., (2014) Evaluation of a new formulation of demineralized bone matrix putty in rabbit posterolateral spinal fusion model. The Spine Journal. September 14(9): 2155-2163

Influx Sponge
  1. Data on file at Xtant Medical.

  2. Kiely, P.D. et al., (2014) Evaluation of a new formulation of demineralized bone matrix putty in rabbit posterolateral spinal fusion model. The Spine Journal. September 14(9): 2155-2163

  3. McLain, R.F., et al. Aspiration of osteoprogenitor cells for augmenting spinal fusion... Journal of Bone and Joint Surgery. 87(12): 2655–2661, 2005.

Influx ProteiOS

1. Data on File, Isto Biologics.

2. Joseph, S., & Edge, L. (2023). Radiographic Evaluation of MI-TLIF Procedures Utilizing Novel Allograft Growth Factor. Jspine, 12, 606.

3. Roh, J. S., Yeung, C. A., Field, J. S., & McClellan, R. T. (2013). Allogeneic morphogenetic protein vs. Recombinant human bone morphogenetic protein-2 in lumbar interbody fusion procedures: A radiographic and economic analysis

4. Kasliwal, M. K., & Deutsch, H. (2012). Clinical and Radiographic Outcomes Using Local Bone Shavings as Autograft in Minimally Invasive Transforaminal Lumbar Interbody Fusion. World Neurosurgery, 78(1–2), 185-190. doi: 10.1016/j.wneu.2011.05.049

Back to top


Precise References
  1. Mautner K et al. A Call for a Standard Classification System for Future Biologic Research: The Rationale for New PRP Nomenclature. PM&R Journal 2015;53-59. 45 South Street

Back to top


Patient Page References
  1. Parrish, WR & Roides, B. Physiology of Blood Components in Wound Healing: an Appreciation of Cellular Co-Operativity in Platelet Rich Plasma Action. J Exerc Sports Orthop 2017; 4:1-14.

  2. Harrell, DB et al. Non-Hematopoietic Essential Functions of Bone Marrow Cells: A Review of Scientific and Clinical Literature and Rationale for Treating Bone Defects. Orthop Rev 2015; 7:5691

  3. Rubin, R & Strayer, DS. Rubin’s patholog: clinicopathologic foundations of medicine. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins 2008; 5th ed.

  4. Podesta L, et al. Treatment of partial ulnar collateral ligament tears in the elbow with platelet-rich plasma. The American Journal of Sports Medicine. 2013;41(7):1689-94. doi: 10.1177/0363546513487979

  5. Franklin, S. et al. The use of platelet-rich plasma for percutaneous treatment of tendinopathies. Operative Techniques in Orthopaedics. 2013;23(2):63-68

  6. Jang SJ, et al. Platelet-rich plasma (PRP) injections as an effective treatment for early osteoarthritis. Eur J Orthop Surg Traumatol. 2013;23: 573-580. doi: 10.1007/s00590-012-1037-5

  7. Haufe SMW and Mork AR. Intradiscal injection of hematopoietic stem cells in an attempt to rejuvenate the intervertebral disc. Stem Cells Dev. 15:136-137. 2006.

  8. Betsch M, et al. Bone marrow aspiration concentrate and platelet rich plasma for osteochondral repair in a porcine osteochondral defect model. PLOS One.  8(8): e71602. 2013.
Back to top