Introducing Influx™ Fibrant, a New Line of Advanced Allograft. Learn More. >>

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Demineralized cancellous allograft

Demineralized bone matrix derived from 100% cancellous bone.

100% Cancellous bone

Influx™ Sponge is a demineralized bone matrix (DBM) derived from 100% cancellous bone. A patented form provides a natural scaffold for cellular ingrowth and exposes bone-growth-inducing proteins to the healing environment. Influx™ Sponge is offered in strip, block, and disc forms.
Due to Influx™ Sponge’s shape memory and malleable properties, each graft form has the ability to fill voids and conform to bony defects, making them an ideal choice for fracture sites, arthrodesis, or as a supplement in spinal fusion devices.
Osteoconductive
Interconnected porosity provides a scaffold for cellular adhesion and vascular ingrowth.
Osteoinductive Potential
Patented demineralization process optimizes the preservation of inherent growth factors that aid in cell differentiation.1
Compressible Handling
Compressible sponge readily conforms to fill a defect, maximizing direct bone to graft contact.
Fluid Retention
Porous matrix allows for adsorption of osteogenic cells from autologous BMA.
Bring the clinical advantages of Influx™ Sponge to your next case.
Download Brochure

Superior fluid retention

Reported Benefits of BMA Absorption 2,3
Creates an osteogenic environment.
Allows for distribution of nutrients
May lead to migration and attachment of more cells
Creates an osteogenic environment.

Influx™ Sponge vs.
traditional bone chips

Compared to traditional bone chips, Influx™ Sponge absorbed three times more bone marrow aspirate (BMA) than traditional crushed cancellous in an in vitro study.1
Download Brochure

Offered in a variety of
sizes and configurations

Influx™ Sponge strip
Size
Product Code
20 x 14 x 7mm
IFLX-OST-20147
26 x 19 x 7mm
IFLX-OST-26197
30 x 10 x 7mm
IFLX-OST-30107
40 x 15 x 5mm
IFLX-OST-40155
50 x 10 x 7mm
IFLX-OST-50107
50 x 20 x 7mm
IFLX-OST-50207
Influx™ Sponge block
Size
Product Code
8mm
IFLX-OBL-08
10mm
IFLX-OBL-10
12mm
IFLX-OBL-12
14mm
IFLX-OBL-14
Influx™ Sponge disc
Size
Product Code
10mm
IFLX-ODC-10
12mm
IFLX-ODC-12
14mm
IFLX-ODC-14
Schedule a case with your Isto sales rep or call (888) 705-ISTO.
To get more information on our Influx Sponge product, contact us today!
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Isto Biologics is the trade name of a single integrated business group that operates through a number of subsidiaries that includes Arteriocyte Medical Systems, Inc., Isto Technologies II, LLC, Progenicare, LLC, Progenicare Therapeutics, LLC, and Advanced Transfusion Services, LLC.

ADVANCED ALLOGRAFT TECHNOLOGY

100% Human Bone

No extraneous carries, fillers or binding agents

Advanced Processing

Enhanced regenerative capacity and handling compared to particulate DBM.1

Terminally Sterilized

Provides device level assurance of safety ( 10 -6 ) 2

Osteoinductive

Proven regenerative capacity by exhibiting all five elements of new bone formation in a validated animal model.2

Osteoconductive

Three dimensional scaffold providing an optimal environment for cellular attachment and proliferation.

Room Temp Storage

Ambient storage for convenient distribution and consignment.

Multiple Sizes and Configurations

Cortical Fibers, Strips and DBM Putty available in multiple sizes.

Multiple Sizes and Configurations for ease-of-use

In a Variety of Applications

Influx™ Demineralized Cortical Bone Fibers

An advanced allograft that combines the regenerative capacity of interconnected fibers with the availability of growth factors endogenous to cortical bone.

Proprietary Processing
  • Proven regenerative capacity in a validated animal model.2
  • Increased patient safety through terminal sterilization
Novel Small Diameter Fibers
  • An ideal scaffold for autologous cells to augment conductive and inductive properties.3
  • Cohesive handling characteristics to provide precise graft placement that is resistant to irrigation.2
  • Handles best when hydrated with blood, BMA, or PRP.
Download Brochure

Influx™ Demineralized Bone Matrix Putty

Fully moldable, 100% demineralized bone graft putty offers optimal regenerative capacity through a proprietary processing of demineralized cortical fibers and demineralized cortical particulate.

Optimal Regenerative Capacity
  • Validated to produce a positive osteoinductive response2
  • Processed for enhanced regenerative capacity compared to particulate DBM1
Ease-of-Use in a Variety of Applications
  • Maintains moldable, cohesive handling characteristics to fill irregular defects and provide lavage resistance.
  • Ready-to-use directly out of packaging with no need for graft preparation or hydration.
Download Brochure

Sizes and Configurations

Influx™ DBM Fibers

Size
1 cc
Size
Size
2.5 cc
5 cc
Size
10 cc

Influx™ DBM Strip  

Size
50 x 10 x 5 mm
Size
Size
50 x 20 x 5 mm
100 x 10 x 5 mm
Size
100 x 20 x 5 mm

Influx™ DBM Putty

Size
1 cc 
Size
Size
2.5 cc
5 cc
Size
10 cc

Influx™ DBM Putty

Size
1 cc 
Size
Size
2.5 cc
5 cc
Size
10 cc