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built to concentrate

The MAGELLAN® is an autologous concentration system that delivers concentrated platelets and cells at the point of care.

Concentrate at the push of a button

Fully Automated

Simple one-button start for ease of use

Closed System

Minimal breaks in sterile barrier promote safety

BioAdaptive Processing

Works with optical sensors to tailor processing parameters based on each patient's hematocrit

Optical Sensors

Identify the cellular fraction to eliminate error and optimize results

Selectable Output

Allows users to define desired therapeutic volumes (3-10 mL per cycle)

deliver  personalized medicine

Every patient has a unique biology with inherent variability, so you need a solution that is customized for each patient. Go beyond the standard of care and deliver a personalized biologic with the Magellan® Autologous Concentration System.

Fully Automated

Fully-automated, closed system produces consistent and reproducible output requiring no manual extraction

Autologous

Optimized to provide high concentrations of platelets, progenitor cells, and platelet-associated growth factors in low final output volume2

Cost-Effective

A single disposable kit can process up to three cycles per patient, offering a cost-effective solution

Customized

Adaptive technology adjusts processing times based on patient’s specific blood and marrow composition

Flexible

Flexibility to process both bone marrow aspirate and whole blood at the point-of-care

Built to Concentrate

Achieves concentration factors up to 14 times baseline9

Proven to Concentrate Viable Progenitor Cells

Data featuring Magellan MAR0Max demonstrates increased concentrations of MSCs & HSCs

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Cell Viability4

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MSC &HSC Concentration9

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Reduction in Red Blood Cells (RBC)9,10

Amplify Essential Growth Factors Up to 14x baseline2

Concentration Factor
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15

PDGF-AB

PDGF-AA

PDGF-BB

TGF-B1

VEGF

FGF-B

EGF

PDGF

Platelet-Derived Growth Factor

TGF B

Transforming Growth Factor - Beta

VEGF

Vascular Endothelial Growth Factor

FGF-B

Fibroblast Growth Factor - Beta

EGF

Epithelial Growth Factor

Concentration Process

Magellan allows clinicians to customize output volumes and concentration factors to meet their patients’ specific needs.

  • A single kit will process 30-60 mL of bone marrow and/or blood to produce a user-defined output volume, ranging between 3-10 mL.
  • Each kit processed three times per patient, offering clinicians a cost-effective solution for processing bone marrow and/or blood.
  • Both PRP and MAR0 kits are available for use with the Magellan system.

Customize Potential Concentration Factors1

High Input Volumes + Low Output Volumes = Highest Concentration1

Users can process 30-60 mL per cycle (up to 180 mL per patient) and select final output volume between 3-10 mL per cycle (up to 30 mL per patient) to customize final concentration.

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Isto Biologics is the trade name of a single integrated business group that operates through a number of subsidiaries that includes Arteriocyte Medical Systems, Inc., Isto Technologies II, LLC, Progenicare, LLC, Progenicare Therapeutics, LLC, and Advanced Transfusion Services, LLC.