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Integrative Bone Matrix™

The Power of Growth Factors

SPARC is a first-of-its-kind Integrative Bone Matrix (IBM) designed to combine the osteoinductive potential of DBM with naturally occurring growth factors derived from proprietary whole bone processing, viable cells, and an osteoconductive scaffold into a single graft.

Meet SPARC

In a category of its own, this multifactor allograft expands the biologic signaling environment and supports a more complete foundation for bone formation.

Osteoinductivity
  • Cortical fiber DBM provides osteoinductive signal1
  • In addition to DBM, proprietary whole-bone processing preserves a broader range of naturally occurring growth factors
Osteoinductivity
Osteoconductivity
  • Cortical fibers undergo a demineralization process providing optimal handling

  • Contribute highly conductive, natural scaffold for new bone generation2
Osteoconductivity
Osteogenicity
  • Proprietary processing preserves osteoprogenitor cells while removing red and white blood cells

  • Bone-derived cells are contained in cancellous chips
Osteogenicity
Ease of Use
  • DMSO-free cryoprotectant: immediately implantable upon thawing in a ready-to-use syringe

  • 10-minute thaw time in room temperature water bath
Ease of Use

A New Category of Bone Graft

SPARC was developed to bridge the gap between traditional cell-focused grafts and growth factor-focused products by supporting multiple mechanisms of bone formation.

Traditional CBMs
Integrative Bone Matrix
Traditional Growth Factor Product
DBM
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Multiple Growth Factors from Whole Bone
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Single Supraphysiological Growth Factor
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Viable Cells
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Scaffold
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Cohesive Handling
varies
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SPARC Fuels Your Fusion

Broader Signaling

Broader signaling profile across multiple biologic pathways.3

Stronger Signaling

Greater availability of key pro-osteogenic growth factors.3

One Complete Graft

Growth factors, viable cells, and
scaffold working together in a single graft.

Expanded & Enhanced Growth Factor Profile

Pro-osteogenic growth factors play a critical role in the biologic processes involved in bone healing, supporting cell recruitment, proliferation, angiogenesis, osteogenic differentiation, and matrix development.4

Many growth factor products are designed to deliver a single supraphysiological signaling molecule, while traditional cellular grafts rely on signaling contribution of DBM which can be limited and weak.5,6

SPARC was designed differently. Through proprietary whole bone processing, SPARC provides a broader range and higher levels of naturally occurring growth factors in a single graft.3


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Clinical Evidence

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Clinical outcomes with SPARC in spinal fusion

View Publication

Clinical outcomes with SPARC in spinal fusion
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Clinical outcomes with SPARC in foot and ankle procedures

View Publication

Clinical outcomes with SPARC in foot and ankle procedures
SPARC (1)
Available Sizes

SPARC is offered in 1 cc, 2 cc, 5 cc, 10cc and 15cc sizes.

Available Sizes

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